Chelsea will face holders and eight-time winners Lyon in the quarter-finals of the Women’s Champions League.
Arsenal will play Bayern Munich, with the Women’s Super League sides unable to be drawn against each other after both winning their groups.
Last year’s runners-up Barcelona play debutants Roma in the last eight while Paris St-Germain take on Wolfsburg.
The quarter-final first legs take place on 21 and 22 March with the return fixtures a week later.
Chelsea will play the winners of the Barcelona-Roma tie in the semi-finals if they get past Lyon.
Chelsea were beaten 4-0 by Barcelona in the 2021 women’s Champions League final.
Arsenal – who beat Lyon 5-1 away on their way to finishing ahead of the Ligue 1 side in their group – will play either PSG or Wolfsburg in the last four should they beat Bayern.
Chelsea failed to progress from their Champions League group last year but had the best pool stage record this season with 16 points from six matches.
Their half of the draw contains the current league leaders in England, Italy, Spain and France, and appears to be the tougher path to the final in Eindhoven on 3 June.
If Chelsea meet Barcelona, it will represent the first time England internationals and Euro 2022 winners Lucy Bronze and Kiera Walsh, who both moved to Spain in the summer from Manchester City, have faced a WSL side in a competitive fixture since leaving their home country.
Arsenal were eliminated at the quarter-final stage by Wolfsburg last season, while Bayern were knocked out by PSG at the same stage.
Facing Arsenal means another Lioness and Euros winner, Georgia Stanway, will face a WSL side for the first time since moving to Bayern from Manchester City last year.
Bayern Munich v Arsenal
Lyon v Chelsea
Roma v Barcelona
PSG v Wolfsburg
PSG/Wolfsburg v Bayern/Arsenal
Chelsea/Lyon v Barcelona/Roma